ProPac Ion Exchange Columns for Protein Analysis Data Sheet.

Dionex - ProPac IMAC Protein and Peptide Column.


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Dionex Propac Wcx 10 Analytical Essay

Separation of Monoclonal Antibodies by Weak Cation.

ProPac WCX-10 column is a weak cation-exchanger with a carboxylate functional group Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semi-prep work Superior Performance for Protein Analysis Ideal for characterization and quality control assessment of MAbs and other proteins.

Dionex Propac Wcx 10 Analytical Essay

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The ProPac WCX-10 column is a weak cation-exchange column designed specifically for high- resolution, high-efficiency analysis of monoclonal antibodies (mAb), and associated variants.

Dionex Propac Wcx 10 Analytical Essay

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ProPac SAX-10 LC column is a strong anion-exchanger with a quaternary amine functional group. Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semiprep work. Superior Performance for Protein Analysis Ideal for characterization and quality control assessment of closely-related protein variants.

Challenge

Part No. 054993 These Dionex ProPac WCX-10 Analytical 4 x 250 mm are in great shape. We are professionals. We encourage you to contact us to speak with.

Thermo Scientific ProPac WCX-10 HPLC Columns, 250mm length.

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Midland Scientific, Inc. - DIONEX 054993.

ProPac WCX-10 column is a weak cation-exchanger with a carboxylate functional group; Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semi-prep work; Superior Performance for Protein Analysis. Ideal for characterization and quality control assessment of MAbs and other proteins; Well-suited for characterization of related protein variants including deamidation and MAb.

Optimal Method Development for Separation of Monoclonal.

The ProPac WCX-10 is the column of choice for the separation of acidic and basic charge variants of monoclonal antibodies (MAb). The choice of buffering eluents and pH play an important role in method development of MAb separation. We tested the separation of MAb using MES (pH 5.6), ACES (pH 6.7) and Tris (pH7.3) eluents.

Solution

However, analytical methods to monitor isomeriza - tion of aspartic acid into iso-aspartic acid (isoAsp) are harder to come by. Valliere-Douglas and colleagues developed a HIC-HPLC method to separate variants containing an isoAsp resi- dues in each of the two light chains of an IgG2 mAb and eluting as two well-resolved pre-main peaks (Fig. 3A).7,8 The method uses two Dionex Propac HIC-10.


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Results

Dionex, the leader of monoclonal antibody analysis, is pleased to announce the release of the MAbPacTM SCX-10 column designed specifically for the exceptionally high-resolution, high-efficiency analysis of monoclonal antibodies and associated variants. This new column's unique nonporous pellicular resin provides unmatched high resolving power, permitting the separation of monoclonal antibody.

Dionex Propac Wcx 10 Analytical Essay

Separation of mAbs molecular variants by analytical.

Dionex is pleased to announce the release of the MAbPacTM SCX-10 column, designed specifically for high-resolution analysis and characterization of monoclonal antibody variants. This new column's unique nonporous pellicular resin provides exceptionally high resolving power, permitting the separation of monoclonal antibody variants that differ by as little as one charged residue.

Dionex Propac Wcx 10 Analytical Essay

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Dionex Propac Wcx 10 Analytical Essay

Thermo Scientific Dionex 054993 PROPAC Wcx-10 Analytical.

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Dionex Propac Wcx 10 Analytical Essay

Thermo Scientific ProPac WCX-10 HPLC Columns.

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Dionex Propac Wcx 10 Analytical Essay

Dionex Releases Column for High-Efficiency, High.

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Dionex Propac Wcx 10 Analytical Essay

Dionex Releases New Column for Exceptionally High.

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